What is segamis?
Selgamis is a prescription cream with the active ingredient Trifaroten, a topical retinoid of the latest generation. It is the first retinoid that is specifically approved for the treatment of acne on the face AND on the hull (breast, shoulders, back).
Trifaroten is a selective RAR-gamma agonist. The retinal receptor gamma is the most common receptor in the skin and plays a central role in skin renewal. Through the targeted activation of this receptor, trifaroten acts particularly effectively against acne.
Selgamis is applied once a day in the evening and is approved for adults and young people from 12 years.
Active Ingredients & Mechanism of Action
Active ingredient: Trifaroten 50 µg/g
Trifarotene acts as a selective retinoid receptor agonist:
Active mechanism: 1. Selective activation of the RAR-gamma receptor Two. RAR-gamma is the dominant retinoid receptor in the skin 3. Normalizes keratinization (horning) 4. Anti-inflammatory action
Effects:
- Solves existing comedons (center)
- Prevents new comedons
- Anti-inflammatory
- Promotes skin renewal
- Reduced pores
speciality: Due to the RAR-gamma selectivity, less skin irritation than in unselective retinoids.
Who is it suitable for?
Selgamis is suitable for:
- Acne vulgaris on the face
- Acne on the hull (bow, back, shoulders)
- Adults and young people from 12 years
- Komedons and inflammatory acne
Special advantage:
- Only retinoid with approval for body acne
- Selective mechanism = better compatibility
Not suitable:
- Severe nodulary/cystic acne
- Pregnancy and breastfeeding
Available Dosages
Selgamis cream 50 μg/g:
- Apply thin once a day
- To all affected areas (face and/or hull)
- Treatment duration: at least 12 weeks
Application area:
- Face: large quantity
- hull: appropriate quantity depending on area
How to Take
Application: 1. Clean the skin and dry well Two. Apply thin layer to all affected areas 3. Apply not only to individual pimples but flat 4. Let in, wash hands
Important notes:
- Apply only in the evening (photosensitization!)
- Use sun protection LSF 30+
- At the beginning, the acne can temporarily deteriorate (Purging)
- Do not use together with irritating products (peelings, alcohols)
Contraindications
Do not apply at:
- Pregnancy (teratogen!)
- Still time
- hypersensitivity to trifarots or components
Preview at:
- Sensitive skin
- eczema or dermatitis in the treatment area
- Strong sun exposure
pregnant: CONTRAINDICES! Effective prevention is necessary. Leave at least 1 month before reception.
Possible Side Effects
Very common (>10%):
- Skin irritation (killing, dandruff, burning) – at the beginning of the treatment, usually improves
Acid (1-10%):
- Itching
- Sunburn (with insufficient sun protection)
Occasionally:
- Contact dermatitis
- Skin swelling
** The initial skin irritation ("retinization reaction") is normal and shows that the drug acts. She usually improves after 2-4 weeks.
Interactions
Reactions:
- Other topical retinoides – do not apply at the same time
- Irritating cosmetics (Peelings, AHA, BHA) – carefully combine
No relevant systemic interaction: Trifaroten has a minimal systemic recording.
Frequently Asked Questions
Similar Medications
Is segamis right for you?
A licensed doctor will review your information and issue a prescription if suitable. Discreet and secure.
Important Notice
This information does not replace medical advice. If you have questions about your health or the suitability of this medication, please consult a doctor or pharmacist.
Important Safety Information
This service operates under German pharmaceutical law (HWG). For risks and side effects, read the package leaflet and consult your doctor or pharmacist. All medications are dispensed from a licensed pharmacy in Germany.