What is OeKolp?
OeKolp contains estriol, a weak natural estrogen that is applied locally in the vaginal range. It is used for the treatment of vaginal atrophiic and dryness, which are caused by oestrogen deficiency after the alternating years.
OeKolp is available as vaginal cream and as vaginal cups (Ovula). Since estriol only acts locally and hardly reaches the bloodstream, it has significantly fewer systemic side effects than oral hormone replacement therapies.
In contrast to systemic HRT preparations, in pure local estriol therapy, no additional gestagen is usually required.
Active Ingredients & Mechanism of Action
Active ingredient: Estriol 0,5 mg / 1 mg
Estriol acts locally on the vaginal mucosa:
Active mechanism:
- Ties to estrogen receptors in vaginal mucosa
- Promotes blood circulation and humidification
- Regenerates the vaginal epithelium
- Lowers the vaginal pH (protection from infections)
Special features of Estriol:
- Less natural estrogen (E3)
- Short-acting – only temporary receptor binding
- No systemic effect on local application
- Usually no stag protection necessary
Effects:
- Relieves vaginal dryness
- Reduces itching and burning
- Improves Lubrication
- Reduced urinary path infection
Who is it suitable for?
OeKolp is suitable for:
- Vaginal atrophie after the change years
- vaginal dryness
- Recurring urinary path infection
- Gender complaints
Advantages:
- Only local effects
- No stag protection required (usually)
- Hardly systemic side effects
- Simple application
Not suitable:
- As a systemic hormone replacement therapy
- Contraindications against estrogens
Available Dosages
OeKolp vaginal cream:
- 1 mg estriol per applicator filling
OeKolp Ovula:
- 0.5 mg of estriol per ovulum
Dosing:
- Initial: 1x daily for 2-3 weeks
- Maintenance: 2-3x per week
- Preferably in the evening before bed
How to Take
Vaginal cream: 1. Screw applicator on tube Two. Press tube to applicator filled 3. Applicator carefully introduce into the vagina 4. Empty cream Five. Clean applicator
Vaginalovula: 1. Remove Ovulum from packaging Two. introduce deep into the vagina 3. Apply in the evening, lay flat
Important:
- Apply night
- Regular, also in case of freedom of appeal (maintenance)
- No self-medication – medical prescription required
Contraindications
Do not apply at:
- Breast cancer (known or suspected)
- estrogen-dependent tumors
- Unexplained vaginal bleeding
- Active thromboemboly
Preview at:
- Endometriosis
- uterus myomas
- Thrombosis risk
Pregnant period: Contraindicated.
** With pure local low dose estriol therapy, the risk of systemic side effects is very low.
Possible Side Effects
**
- Local burning or itching (in the beginning)
- Easy drain
Occasionally:
- Breast tensions
- Light lubrication bleeding
Very rare:
- Systemic estrogen effects (in case of overdose)
** Local reactions usually improve after the first applications.
Interactions
No clinically relevant interactions with local application.
** Can affect the effectiveness of latex condoms (oil-containing cream). Use alternatives.
Frequently Asked Questions
Similar Medications
Is OeKolp right for you?
A licensed doctor will review your information and issue a prescription if suitable. Discreet and secure.
Important Notice
This information does not replace medical advice. If you have questions about your health or the suitability of this medication, please consult a doctor or pharmacist.
Important Safety Information
This service operates under German pharmaceutical law (HWG). For risks and side effects, read the package leaflet and consult your doctor or pharmacist. All medications are dispensed from a licensed pharmacy in Germany.