What is olmesartan?
Olmesartan is a potent AT1 receptor blocker (Sartan) with a strong blood pressure-lowering effect. It is available as a mono preparation and in various combinations: Olmetec®, Olmetec Plus® (with HCT), Sevikar (with Amlodipine) and Vocado® HCT.
Olmesartan is often used when a strong reduction in blood pressure is required and can be combined well with other active ingredients.
Active Ingredients & Mechanism of Action
Active ingredient: Olmesartan medoxomil
Olmesartan blocks the AT1 receptor:
Active mechanism:
- Selective and potent AT1 receptor blockade
- Used as Prodrug (Olmesartan medoxomil)
- Intestine converted to active Olmesartan
- Strong and persistent blood pressure reduction
Clinical effect:
- belongs to the more blood pressure-lowering sartans
- duration of action: 24 hours
- Good protection even in the morning hours
Who is it suitable for?
Olmesartan is suitable for:
- Adults with high blood pressure
- Patients who need more blood pressure reduction
- In combination with amlodipine and/or HCT
Especially suitable for:
- Treatment-resistant high blood pressure
- Need for combination therapy
Not suitable:
- Pregnancy and breastfeeding
- Gallenwegsobstruction
- Heavy liver failure
Available Dosages
High blood pressure:
- Start dose: 10 mg once a day
- usual dose: 20 mg once a day
- Maximum dose: 40 mg daily
Available starches:
- 10 mg, 20 mg, 40 mg tablets
Combination preparations:
- Olmesartan + HCT (Olmetec Plus®)
- Olmesartan + Amlodipine (Sevikar)
- Olmesartan + Amlodipin + HCT (Vocado® HCT)
How to Take
Intake:
- Once a day, always at the same time
- Independent meals
- Take with water
**
- Regular blood pressure control
- Laboratory controls (animal, potassium)
- Don't suddenly stop
- Drink enough
Contraindications
**Olmesartan must not be taken at:* *
- hypersensitivity to Olmesartan
- Pregnancy and breastfeeding
- Gallenwegsobstruction
- At the same time with aliens in diabetes
Preview at:
- Kidney failure
- Kidney artery stenosis
- Hyperkaliemia
- Dehydration
- Aortenstenose
Special warning: In rare cases, Olmesartan can cause a spue-like enteropathy (heavy diarrhea with weight loss). In case of chronic diarrhea in Olmesartan inform the doctor.
pregnant: contraindicated throughout pregnancy.
Possible Side Effects
Acid (1-10%):
- Squeeze
- Headaches
- Increased blood fat levels
** Occasionally (0,1-1%):* *
- fatigue
- Gastrointestinal complaints
- Hyperkaliemia
- Kidney malfunction
- Husten (rare)
Selten, but important:
- Sprue-like enteropathy (chronic diarrhea, weight loss)
- Angioedema
- Liver malfunction
** In the case of chronic, unexplained diarrhea in Olmesartan, a spue-like enteropathy should be considered. After decommissioning, the symptoms are better.
Interactions
Contracted:
- Aliskiren in diabetes or kidney failure
Preview at:
- Potassium-saving diuretics → Hyperkaliemia
- NSAR → reduced effect
- Lithium → raised mirrors
- Colesevelam → reduced Olmesartan recording
** Colesevelam (Gallen Acid Binder) can reduce the absorption of Olmesartan. Time distance recommended.
Frequently Asked Questions
Similar Medications
Is olmesartan right for you?
A licensed doctor will review your information and issue a prescription if suitable. Discreet and secure.
Important Notice
This information does not replace medical advice. If you have questions about your health or the suitability of this medication, please consult a doctor or pharmacist.
Important Safety Information
This service operates under German pharmaceutical law (HWG). For risks and side effects, read the package leaflet and consult your doctor or pharmacist. All medications are dispensed from a licensed pharmacy in Germany.