What is Telmisartan?
Telmisartan is an AT1 receptor blocker with the longest half-life of all sartans (about 24 hours). This means a particularly uniform 24-hour blood pressure protection, even in the critical early hours.
Known brand names are Kinzalmono® and Micardis®. Telmisartan is also available in combination with hydrochlorothiazide (Micardis® Plus). It also has a mild PPAR-gamma activation, which can have a positive effect on metabolism.
Active Ingredients & Mechanism of Action
Active ingredient: Telmisartan
Telmisartan blocks the AT1 receptor particularly long-lasting:
Active mechanism:
- High-selective and long-lasting AT1 blockade
- Longest half-life of all Sartane (about 24 hours)
- Lipophile – high tissue penetration
Additional properties:
- Mild PPAR-gamma activation (substance-promoting)
- Can easily improve insulin resistance
- Cheap effects on lipid metabolism
Clinical meaning: In the ONTARGET study, Telmisartan was equivalent to the ACE inhibitor Ramipril in high-risk patients.
Who is it suitable for?
Telmisartan is suitable for:
- Adults with high blood pressure
- cardiovascular prevention in high risk patients
- Patients who need a reliable 24-hour action
Especially recommended at:
- Early blood pressure (low blood pressure)
- Metabolic syndrome
- Patients who do not use Ramipril
Not suitable:
- Pregnancy and breastfeeding
- Gallenwegsobstruction
- Heavy liver failure
Available Dosages
High blood pressure:
- Start dose: 40 mg once a day
- usual dose: 40-80 mg once a day
- Maximum dose: 80 mg daily
Cardiovascular prevention:
- 80 mg once a day
Available starches:
- 20 mg, 40 mg, 80 mg tablets
Combination:
- Telmisartan + Hydrochlorothiazid (Micardis® Plus)
How to Take
Intake:
- Once a day, if possible in the morning
- Independent meals
- Take with water
- Do not share or chew tablet
**
- Regular blood pressure controls
- Laboratory controls (animal, potassium)
- Do not drop abruptly
Contraindications
**Telmisartan must not be taken at:* *
- hypersensitivity to Telmisartan
- Pregnancy and breastfeeding
- Gallenwegsobstruction
- Heavy liver failure
- At the same time with aliens in diabetes
Preview at:
- Kidney failure
- Kidney artery stenosis
- Hyperkaliemia
- Primary hyperaldosteronism
pregnant: Strikt contraindicates throughout pregnancy.
Possible Side Effects
** Occasionally (0,1-1%):* *
- Squeeze
- urinary tract infections
- infections of the upper respiratory tract
- Back pain
- Gastrointestinal complaints
Selten:
- Hyperkaliemia
- Kidney function reduction
- Angioedema
- Liver malfunction
Good tolerated: Telmisartan has shown in studies a compatibility that is hardly above placebo levels. It is one of the best tolerated blood pressure medications.
Interactions
Contracted:
- Aliskiren in diabetes or kidney failure
Preview at:
- Potassium-saving diuretics → Hyperkaliemia
- NSAR → reduced effect
- Lithium → raised mirrors
- Digoxin → mirror increase possible
Fabric change: Telmisartan is not degraded via CYP enzymes, so little interactions about this path.
Frequently Asked Questions
Similar Medications
Is Telmisartan right for you?
A licensed doctor will review your information and issue a prescription if suitable. Discreet and secure.
Important Notice
This information does not replace medical advice. If you have questions about your health or the suitability of this medication, please consult a doctor or pharmacist.
Important Safety Information
This service operates under German pharmaceutical law (HWG). For risks and side effects, read the package leaflet and consult your doctor or pharmacist. All medications are dispensed from a licensed pharmacy in Germany.