What is Testotop?
Testotop® is a testosterone gel for external use in adult men with proven testosterone deficiency. It contains testosterone and is applied to the skin once daily to restore physiological hormone levels.
Testotop® complements the available transdermal testosterone products and offers an alternative to Testogel®, Testavan®, and Tostran®.
Active Ingredients & Mechanism of Action
Active ingredient: Testosteron
Mechanism of action:
- Testosterone absorbed transdermally through the skin
- Restoration of normal androgen levels
- Action via androgen receptors in muscle tissue, bone, the CNS, and the genital organs
Activity profile:
- Even release throughout the day
- Stable blood levels after a few days of regular use
- Clinical improvement of symptoms after 2–12 weeks
Effects: Improvement in libido, erectile function, energy levels, muscle mass, and bone density.
Who is it suitable for?
Testotop® is suitable for:
- Adult men with confirmed hypogonadism
- As an alternative if other testosterone gels are not tolerated or preferred
Not suitable:
- Women and children
- Prostate cancer or breast cancer in men
- Severe organ failure (heart, liver, kidney)
- Polycythemia
- Active wish to have children
Available Dosages
Dosage:
- Recommended starting dose: 125 mg testosterone (5 g gel) once daily
- First check of the testosterone blood level about 1 week after starting, in the morning before the next application
- Adjustment by the doctor: reduction from 125 mg to 62.5 mg (2.5 g gel) if the level is above the normal range, or an increase of 62.5 mg (2.5 g gel) if it is below
- Maximum dose: 250 mg testosterone (10 g gel) per day
Monitoring:
- Regular blood level checks
- Monitor hematocrit, PSA, and liver function tests
- Target: testosterone in the mid-normal range
How to Take
Application:
- Once daily, preferably in the morning
- Apply to clean, dry, intact skin
- Recommended application areas as stated in the package insert
- Wash hands thoroughly after applying
Important notes:
- Avoid skin contact at the application site with women and children
- Apply at least 2 hours before showering/swimming
- Cover the area with clothing
- Do not apply to damaged or inflamed skin
Contraindications
Testotop® must not be used in cases of:
- Prostate cancer or suspected prostate cancer
- Breast cancer in men
- Hypersensitivity to testosterone
- Polycythemia
Use with caution in:
- Severe heart, liver or kidney failure
- Sleep apnea
- BPH
- Epilepsy
- Diabetes mellitus
- Cardiovascular disease
Possible Side Effects
Common (1–10%):
- Skin irritation at the application site
- Erythrocytosis / increased hematocrit
- Increase in PSA
- Acne
Uncommon (0.1–1%):
- Mood swings
- Gynecomastia
- Weight gain
- Hair loss
- Headache
Rare:
- Polycythemia
- Elevated liver function tests
- Worsening of sleep apnea
Frequently Asked Questions
The choice depends on personal preferences: application site, dose dispenser, tolerability, and price. Your doctor will help you choose.
Testosterone gel may only be used if a testosterone deficiency has been proven and under medical supervision. Even then, side effects can occur, most commonly skin reactions at the application site and emotional symptoms such as mood swings. Regular blood tests (hematocrit, PSA, liver) are important. Risks exist in cases of misuse or use without a proven deficiency.
Yes, switching from testosterone injections (e.g., Nebido®) to a gel is possible. The switch should be supervised by a doctor, as the timing and the starting dose must be determined individually.
Similar Medications
Is Testotop right for you?
A licensed doctor will review your information and issue a prescription if suitable. Discreet and secure.
Important Notice
This information does not replace medical advice. If you have questions about your health or the suitability of this medication, please consult a doctor or pharmacist.
Important Safety Information
This service operates under German pharmaceutical law (HWG). For risks and side effects, read the package leaflet and consult your doctor or pharmacist. All medications are dispensed from a licensed pharmacy in Germany.





