What is Avanafil?
Avanafil is the active ingredient of the Spedra brand product and has also been available as a generic product since the patent procedure. It is the youngest and fastest PDE-5 inhibitors on the market.
The generics contain the same active ingredient and offer the same fast effect as the original, but at a cheaper price.
The action can already take place after 15 minutes – significantly faster than in Sildenafil (30-60 min) or Tadalafil (30 min).
Active Ingredients & Mechanism of Action
Active ingredient: Avanafil
Avanafil inhibits the enzyme phosphodiesterase-5 (PDE-5) in the swelling body. This keeps the messenger substance cGMP active longer, the blood vessels relax and more blood can flow into the penis.
Advantages of Avanafil:
- Fastest absorption of all PDE-5 inhibitors
- High selectivity for PDE-5
- Possible fewer side effects
Who is it suitable for?
Avanafil generics are suitable for men who:
- Need quick action
- Want to save costs (more favourable than Spedra)
- Miscellaneous PDE-5 inhibitors
Available Dosages
- 50 mg
- 100 mg
As with Spedra: start with 100 mg, adjustment depending on the effect.
How to Take
15-30 minutes before intercourse, with or without food.
Contraindications
Identical with Spedra: No combination with nitrates, contraindicated in severe heart disease.
Possible Side Effects
Headache, flush, clogged nose, dizziness – as with all PDE-5-inhibitors.
Frequently Asked Questions
Similar Medications
Is Avanafil right for you?
A licensed doctor will review your information and issue a prescription if suitable. Discreet and secure.
Important Notice
This information does not replace medical advice. If you have questions about your health or the suitability of this medication, please consult a doctor or pharmacist.
Important Safety Information
This service operates under German pharmaceutical law (HWG). For risks and side effects, read the package leaflet and consult your doctor or pharmacist. All medications are dispensed from a licensed pharmacy in Germany.





