What is aniline?
Zindaclin is a prescription gel with the active ingredient clindamycin, a lincosamide antibiotic. It is used for topical treatment of light to moderately heavy inflammatory acne vulgaris.
Clindamycin acts against the acne-causing bacteria Cutibacterium acnes and reduces the inflammatory reaction in the skin. It should ideally be used in combination with benzoyl peroxide or a retinoid to prevent the development of resistance.
Zindaclin is applied once a day and is approved for adults and young people from 12 years.
Active Ingredients & Mechanism of Action
Active ingredient: Clindamycin 1%
Clindamycin Antibacterial:
Active mechanism:
- Inhibits bacterial protein biosynthesis (50S subunit of ribosomes)
- Bacteriostatic against Cutibacterium acnes
- Reduces the concentration of free fatty acids on the skin
- Anti-inflammatory side effect
Additional effects:
- Reduces the neutrophil chemotaxis
- Complement activation
- Works indirectly against comedons by reducing inflammation
Time:
- First improvement: 2-4 weeks
- Optimum effect: 6-8 weeks
Who is it suitable for?
Zindaclin is suitable for:
- Light to moderate inflammatory acne
- Papulo pussy acne
- Adults and young people from 12 years
Important:
- Best in combination with benzoyl peroxide (against resistance)
- Or in combination with a retinoid
Not suitable:
- Heavy acne (systemic therapy required)
- Non-inflammatory acne (pure Komedons)
- Monotherapy over a longer period of time (resistance risk)
Available Dosages
Zindaclin Gel 1%:
- Apply thin to affected skin areas once a day
- duration of treatment: 6-8 weeks, maximum 12 weeks
Combination recommended:
- Morning Zindaclin + evening benzoyl peroxide or retinoid
- Or combination preparation like Duac Gel
How to Take
Application: 1. Clean face and dry Two. Apply thin layer to inflamed areas 3. Let's move 4. Wash hands
Combination therapy:
- Morning: Zindaclin
- Evening: benzoyl peroxide or retinoid
- Replace time, not apply at the same time
Important:
- Not on open wounds or damaged skin
- Avoid contact with eyes and mucous membranes
Contraindications
Do not apply at:
- hypersensitivity to clindamycin or lincomycin
- Colitis ulcerosa or Morbus Crohn in prehistory
- Antibiotics-associated colitis in history
Preview at:
- Sensitive skin
- Atopic dermatitis
pregnant: Can be applied after strict indication.
Style time: Application possible, not in the chest area.
Possible Side Effects
Acid (1-10%):
- dry skin
- Skin irritation
- Burning or itching
Occasionally:
- dandruff
- Oily skin
- Contact dermatitis
Selten:
- Gastrointestinal complaints (in case of systemic resorption)
- Pseudomembranous colitis (very rare for topical use)
Interactions
Reactions:
- Erythromycin (topic) – antagonistic action, do not combine
- Neuromuscular blockers – theoretical effect gain
Ingenious combination:
- Benzoyl peroxide (prevents resistance)
- Retinoides (supplementary effect)
Frequently Asked Questions
Similar Medications
Is aniline right for you?
A licensed doctor will review your information and issue a prescription if suitable. Discreet and secure.
Important Notice
This information does not replace medical advice. If you have questions about your health or the suitability of this medication, please consult a doctor or pharmacist.
Important Safety Information
This service operates under German pharmaceutical law (HWG). For risks and side effects, read the package leaflet and consult your doctor or pharmacist. All medications are dispensed from a licensed pharmacy in Germany.