What is aldara?
Aldara® is a cream with the active ingredient Imiquimod (5%), which is used for the treatment of external genital and perianal warts (Condylomata acuminata, fig warts) in adults. These warts are caused by human papilloma viruses (HPV), usually the types 6 and 11.
Imiquimod is an immune modulator – it activates the body's immune system to combat the viruses and to reject the warts. The cream is applied by the patient himself at home, which is a great advantage over doctor treatments.
Aldara® is also approved for the treatment of actinic keratose and superficial basal carcinomas.
Active Ingredients & Mechanism of Action
Active ingredient: Imiquimod (5 %)
Active mechanism:
- Imiquimod activates Toll-like receptor 7 (TLR7) on immune cells
- Stimulates the production of interferon-alpha and other cytokines
- Local immune response is enhanced
- Virus infected cells are detected and destroyed
Immunological cascade:
- Activation of dendritic cells and macrophages
- Enhanced T cell response against HPV infected cells
- Induces apoptosis (programmed cell death) of wart cells
- Long-term immune memory formation
Advantages:
- Low fall rate (about 13–19 %) compared to destructive methods
- Self-application at home possible
- also treats subclinical (non-visible) HPV lesions in the treatment area
Who is it suitable for?
Aldara® is suitable for:
- Adults with outer genital and perianal warts
- Warts on normal skin (not on mucous membranes)
- Self-treatment at home
Not suitable:
- Internal (vaginal, cervical, urethral, anale) warts
- Children under 18 (for this indication)
- Pregnancy (inappropriate data)
- Immunosuppressed patients (restricted action)
- Open wounds or inflamed skin
Available Dosages
Genital warnings:
- Apply three times a week (e.g. Monday, Wednesday, Friday)
- Apply before bed
- Wash off after 6-10 hours
- Maximum treatment time: 16 weeks
Application quantity:
- Apply thin layer to warts
- 1 bag for an area of about 20 cm2
- Only apply to outer warts
Current:
- First improvement after 4-8 weeks
- Complete healing after 8–16 weeks
- redness and light inflammation are signs of action
How to Take
Application: 1. Wash your hands before bed Two. Apply thin layer Aldara® to warts 3. Gently rub until the cream is drawn in 4. Wash hands thoroughly Five. The next morning (after 6–10 hours) wash with mild soap and water
Important notes:
- Do not use under the Occlusive Association
- No intercourse as long as the cream is on the skin
- Condoms and diaphragms can be weakened by the cream
- With strong skin reaction: 1–2 applications leave
- Do not apply to open wounds or mucous membranes
Contraindications
**Aldara® must not be used at:* *
- hypersensitivity to imiquimod
- Inside genital warts
Preview at:
- Autoimmune diseases
- Organ-transplanted/immune-suppressed
- Untreated preskin gene (Phimose)
- Pregnancy and breastfeeding
Do not apply to:
- mucous membranes (vaginal, anal inside, urethral)
- Open wounds
- Sun damaged skin at the same time
Possible Side Effects
**Very common (> 10 %):* *
- Local skin reactions: redness, erosion, dandruff, swelling, crust formation
- These reactions are signs of immune activation and desired!
Family (1–10 %):
- Burn, itching at the job site
- Headaches
- Flu-like symptoms
- muscle pain
Occasionally:
- Pain at the job site
- Local infection
- lymph node swelling
** Mild to moderate skin reactions are normal and a sign of efficacy. In case of strong reactions (open places, severe pain) take a break of several days.
Frequently Asked Questions
Similar Medications
Is aldara right for you?
A licensed doctor will review your information and issue a prescription if suitable. Discreet and secure.
Important Notice
This information does not replace medical advice. If you have questions about your health or the suitability of this medication, please consult a doctor or pharmacist.
Important Safety Information
This service operates under German pharmaceutical law (HWG). For risks and side effects, read the package leaflet and consult your doctor or pharmacist. All medications are dispensed from a licensed pharmacy in Germany.




