What is pridinol?
Pridinol is a centrally and peripherally effective muscle relaxant that is sold under the brand name Myditin®. It is used for treating acute painful muscle tensions, especially in back and neck pain.
The active ingredient has both anticholinergic and antihistaminergic properties and has muscle-relieving mechanisms over several mechanisms. Pridinol has been used in Germany for decades.
It is usually prescribed as short-term therapy in combination with analgesics and physiotherapy.
Active Ingredients & Mechanism of Action
Active ingredient: Pridinolmesilat
Pridinol has several mechanisms:
Active mechanisms:
- Anticholinerg: Inhibits the cholinerge transmission at the motor end plate
- Central muscle relaxation: Inhibits polysynaptic reflexes in spinal cord
- Analgetic: Own pain relief effect (via glutamate receptors)
speciality:
- Works both centrally and peripheral muscle relax
- Has an independent pain relief effect
- Anticholine side effects note
Pharmacokinetics:
- Effect entry: 30–60 minutes
- duration of action: 4–6 hours
- half-life: approx. 4 hours
Who is it suitable for?
Pridinol is suitable for:
- Acute painful muscle tensions
- Lumbago
- Torticollis (acute slate)
- Painful muscle hardening in the back and neck area
Used as:
- Accompanying medication for analgesics
- Short-term therapy (up to 2–3 weeks)
- Supplement to physiotherapy
Not suitable:
- At Engangle glaucoma
- In prostate adenom with residual harness
- At Megakolon
- At Myasthenia gravis
Available Dosages
Tablets:
- 3 mg
Use dosage (adults):
- 1–2 tablets 3 times a day
- usual daily dose: 9–18 mg
- Maximum daily dose: 18 mg (6 tablets)
Language:
- Short term: 1–3 weeks
- Not recommended for long-term use
How to Take
Intake:
- Take tablets unzerkaut with water
- Independent meals
- 3 times a day at regular intervals
Important notes:
- Restriction of traffic
- No alcohol (reinforced sedation)
- Be careful with heat (anticholinerg → reduced welding production)
- Convene dryness with water or sugar-free gum
Contraindications
**Pridinol must not be taken at:* *
- Engangle glaucoma (Green Star)
- Prostataadenome with residual urine formation
- Megacolon
- Myasthenia gravis
- Tachycardia heart rhythm disorders
- hypersensitivity to Pridinol
Preview at:
- prostate enlargement
- Harnverhalt cleaning
- Constipation tendency
- Fever (reduced heat dissipation)
- Elderly patients (strap, confusion)
Pregnant period: Not recommended due to insufficient data.
Possible Side Effects
Fatigue (anticholine effects):
- Mouth dryness
- tiredness, sleepiness
- Accomodation dysfunction (nearly impaired)
- Blocking
- Harnverhalt
Occasionally:
- Tachycardia (fast heartbeat)
- Gastrointestinal complaints
- Squeeze
- confusion (especially in older patients)
Selten:
- Allergic skin reactions
- Glaukomanfall (with predisposed patients)
** The anti-choline side effects limit the use in older patients.
Interactions
Enhanced anticholinergic action with:
- Tricyclic antidepressants
- Antihistamines
- Neuroleptics
- antiparkinsonants (e.g. biperids)
Intensified sedation with:
- Alcohol
- benzodiazepines
- Opioids
- Antihistamines
Preview at:
- MAO inhibitors
- Other centrally acting drugs
Frequently Asked Questions
Similar Medications
Is pridinol right for you?
A licensed doctor will review your information and issue a prescription if suitable. Discreet and secure.
Important Notice
This information does not replace medical advice. If you have questions about your health or the suitability of this medication, please consult a doctor or pharmacist.
Important Safety Information
This service operates under German pharmaceutical law (HWG). For risks and side effects, read the package leaflet and consult your doctor or pharmacist. All medications are dispensed from a licensed pharmacy in Germany.