Estramon conti

ESTRAMON conti is a patch for hormone replacement therapy (HRT). It contains two female sex hormones, the estrogen estradiol and the progestogen norethisterone acetate, which are released through the skin.

It is used in women after menopause whose last menstrual period was at least one year ago, to relieve symptoms such as hot flashes — when these significantly affect daily life.

The patch is changed twice a week and used without a break.

Estradiol replaces the estrogen that the body produces in smaller amounts after menopause, thereby relieving symptoms such as hot flashes.

Norethisterone acetate is a progestogen. It protects the lining of the uterus from excessive thickening, which can occur with estrogen alone.

Both hormones are released evenly through the skin.

ESTRAMON conti is suitable for:

• Women after menopause whose last menstrual period was at least one year ago
• Symptoms such as hot flashes that significantly affect daily life

Note:

• Only limited experience is available in women over 65 years of age.

ESTRAMON conti 30/95 µg/24 h:

• 1 patch contains 3.2 mg estradiol and 16 mg norethisterone acetate and releases 30 µg estradiol and 95 µg norethisterone acetate per 24 hours.
• A new patch 2 times a week, i.e., every 3 or 4 days
• Continuously, without a break

Where the patch goes:

• On an area of skin that folds little during movement, e.g., on the side of the thigh
• NOT on the breasts
• Not on reddened or injured skin; preferably a hairless area
• Not where clothing fits tightly or under a hem

Applying:

• Clean the skin thoroughly beforehand; no body lotion, no oil, shower gel, or sunscreen — the skin must be dry and free of grease
• Apply the patch smoothly without air bubbles and press it on with the palm of your hand for 1 minute
• Do not let the desiccant in the pouch come into contact with the skin

In everyday life:

• Bathing and showering are possible with the patch; in very hot bath water or in the sauna it may come off
• Sunlight or tanning beds can impair effectiveness
• If a patch comes off, apply a new one and change it on the usual day
• Apply each new patch to a different area of skin; fold used patches with the adhesive side inward

ESTRAMON conti must not be used in cases of:

• Breast cancer, including past or suspected breast cancer
• Estrogen-dependent cancer, e.g., of the lining of the uterus, or a corresponding suspicion
• Vaginal bleeding of unclear cause
• Untreated thickening of the lining of the uterus
• Existing or past thrombosis or pulmonary embolism
• Blood clotting disorders (e.g., protein C, protein S, or antithrombin deficiency)
• Diseases caused by blood clots in the arteries, e.g., heart attack, stroke, angina pectoris
• Liver disease, as long as liver values are not normal
• Porphyria
• Allergy to estradiol, norethisterone acetate, soy, peanut, or any of the other ingredients

If any of these conditions occurs for the first time during use, stop treatment immediately and have it evaluated by a doctor.

Very common (more than 1 in 10 people treated):

• Headache
• Skin reactions at the application site
• Breast tension and pain, abnormal bleeding

Common (up to 1 in 10 people treated):

• Depression, nervousness, mood swings
• Dizziness, insomnia
• Nausea, flatulence, abdominal pain, diarrhea
• Acne, rash, itching
• Back pain, fluid retention, weight gain
• Irregular bleeding, vaginal infection

Uncommon (up to 1 in 100 people treated):

• Migraine, increased blood pressure, varicose veins, vomiting

The complete list can be found in the package leaflet.

Tell your doctor about all medicines you use. Details on interactions can be found in the package leaflet.