What is Alfatradiol?
Alfatradiol (17α-estradiol) is a topical medication for hereditary hair loss. Unlike finasteride, it is applied to the scalp and acts locally.
Well-known product: Ell-Cranell.
Alfatradiol has only a low estrogenic hormonal effect and is used in men and women.
Active Ingredients & Mechanism of Action
Active ingredient: Alfatradiol (17α-Estradiol)
Alfatradiol inhibits 5-alpha reductase locally in the scalp:
- Less DHT directly at the hair follicle
- Penetrates the skin well. As no blood level measurements are available, it must be assumed that practically the entire applied amount can enter the body
- Only very low binding to the estrogen receptor
Who is it suitable for?
- Men AND women with hereditary hair loss
- Men who want to avoid finasteride side effects
- As a complement to other treatments
Available Dosages
- 0.025% alfatradiol solution
- 1x daily, 3 ml applied to the scalp
How to Take
Apply once daily to the dry scalp, preferably in the evening.
Contraindications
Hypersensitivity, scalp disorders, pregnancy.
Possible Side Effects
Local irritation (rare), itchy scalp.
Frequently Asked Questions
The body of research is less extensive. Alfatradiol appears to be somewhat less effective than finasteride.
Similar Medications
Is Alfatradiol right for you?
A licensed doctor will review your information and issue a prescription if suitable. Discreet and secure.
Important Notice
This information does not replace medical advice. If you have questions about your health or the suitability of this medication, please consult a doctor or pharmacist.
Important Safety Information
This service operates under German pharmaceutical law (HWG). For risks and side effects, read the package leaflet and consult your doctor or pharmacist. All medications are dispensed from a licensed pharmacy in Germany.





