What is Doloproct® (Fluocortolon/Lidocain)?
Doloproct® is a prescription combination preparation for treating hemorrhoids and other inflammatory diseases of the anal region. It contains two fluocortolon ester (fluoroocortolon pivalate and fluocortolonhexanoate) as a corticosteroid component and Lidocain as a local anesthetic.
The combination of two fluocortolon esters with different duration of action ensures rapid action (pivalate) and a sustained action (hexanoate). Lidocain anesthetizes the affected area and relieves pain and itching immediately.
Doloproct® is available as rectal ointment and as suppositories and is used in hemorrhoids grade I–II, anal fissures, anal eczema and proctitis.
Active Ingredients & Mechanism of Action
Active ingredient: Fluocortolonpivalat / Fluocortolonhexanoat / Lidocainhydrochlorid
Doloproct® has two mechanisms:
1. Fluocortolon (Kortikosteroid):
- Strong local anti-inflammatory effect
- Two esters with different duration of action:
- Fluocortolonpivalat: Fast action
- Fluocortolonhexanoate: Long-lasting action
- Reduces swelling, redness and inflammation
- Inhibits the release of inflammatory mediators
- Reduces itching and burning
2. Lidocain (local anesthetic):
- Blocks the sodium channels of the nerve fibers
- Immediate local anesthesia
- relieves pain, burning and itching
- Effects within minutes
- duration of action: 1–2 hours
Combined action: Lidocain immediately relieves the acute symptoms, while Fluocortolon treats inflammation and ensures continued improvement.
Who is it suitable for?
Doloproct® is suitable for:
- Hemorrhoids degree I and II
- Analeczem (Ekzem in the anal area)
- Analfissures (superficial tears)
- Proctitis (inflammation of the end intestine)
Especially suitable for:
- Acute complaints with pain and itching
- inflammatory hemorrhoid strokes
- Short-term treatment of anal complaints
Not suitable:
- Hemorrhoids degree III–IV (medical treatment/OP necessary)
- Mushroom or virus infections in the anal area (e.g. herpes, candidose)
- Tuberculosis or syphilis in scope
- Long-term application (max. 2–4 weeks)
Available Dosages
Rectal ointment:
- apply 2–3 × daily thin
- The first day may be more frequent (up to 4 ×)
- After improvement: reduce dose to 1 × daily
- Application time: max 2–4 weeks
Suppositories:
- 1 cups 2–3 × daily introduce rectal
- The first day up to 4 × daily possible
- After improvement: 1 × daily
- Application time: max 2–4 weeks
Important:
- Apply no longer than 4 weeks uninterrupted
- Reducing dose and frequency step by step
- Do not drop abruptly after prolonged use
Available dosage forms:
- Doloproct® Rektalsalbe (with applicator)
- Doloproct® cups
How to Take
Rectal ointment:
- Before application gently clean the anal region
- apply thin layer to the affected area
- In inner hemorrhoids: screw applicator on the tube and insert ointment rectally
- After application wash hands
Chapters:
- Introduction after the chair and cleaning
- Dissolve cups from the packaging
- Insert into the after (rounded end forward)
- Apply as possible after stool
Important notes:
- Not with open, wet wounds without medical instruction
- In case of ongoing complaints after 1 week: Medical control
- Do not combine with latex condoms (Lidocain can damage latex)
- No long-term application due to skin atrophiic risk (corticosteroid)
Contraindications
**Doloproct® must not be used at:* *
- hypersensitivity to fluocortolone, lidocaine or other components
- Virus infections in the field of application
- Mushroom infections (candiosis) in anal area
- Tuberculosis or syphilis in scope
- Bacterial skin infections (Impetigo) in the area
Preview at:
- Diabetes mellitus (Corticosteroid can affect blood sugar)
- Long-term application (Hautatrophie, Teleangiectasis)
- Pregnancy and breastfeeding (only after medical weighing)
- Large-area application (increased systemic recording)
pregnant: Only after strict use-risk weighing, especially in the 1st trimester. Do not apply over a long period of time.
Possible Side Effects
** Occasionally (0.1-1 %):* *
- Burning at the application site
- Itching at the application site
- Contact dermatitis
For long-term use:
- skin atrophie (skin dilution)
- Teleangiectasia (visible small blood vessels)
- Striae (stretching strips)
- Perianal dermatitis
- Increased susceptibility to infection in the scope of application
Selten:
- allergic reactions to lidocaine or fluocortolon
- Systemic cortisone effects (only with very large-area/long-term use)
** For normal short-term application (max. 2–4 weeks), side effects are rare and usually mild. The skin atrophie travel is mainly used for longer periods.
Interactions
Clinical interactions: Systemic interactions are unlikely in the case of proper rectal application, since systemic uptake is low.
Theoretically possible:
- Other local anaesthetics: additives
- Class I Antiarrhythmics: Theoretical amplification by Lidocain
- Latex condoms: can be damaged by the ointment base
** Due to the local application and low systemic absorption, clinically relevant drug interactions at Doloproct® are extremely rare.
Frequently Asked Questions
Similar Medications
Is Doloproct® (Fluocortolon/Lidocain) right for you?
A licensed doctor will review your information and issue a prescription if suitable. Discreet and secure.
Important Notice
This information does not replace medical advice. If you have questions about your health or the suitability of this medication, please consult a doctor or pharmacist.
Important Safety Information
This service operates under German pharmaceutical law (HWG). For risks and side effects, read the package leaflet and consult your doctor or pharmacist. All medications are dispensed from a licensed pharmacy in Germany.