What is Cerazette?
Cerazette is an estrogen-free contraceptive pill that contains only the gestagen Desogestrel. It belongs to the so-called minipills, but differs from older minipills by their ability to reliably suppress ovulation.
Unlike combination pills, Cerazette does not contain estrogen. This makes them suitable for women who do not tolerate estrogen or where estrogen is contraindicated – for example breastfeeding mothers, smokers over 35 or women with migraines with aura.
Prevention safety is much better than older minipills with a Pearl index of about 0.4.
Active Ingredients & Mechanism of Action
Active ingredient: Desogestrel 0,075 mg
Cerazette works by several mechanisms:
Progress prevention: Unlike older minipills, Desogestrel reliably inhibits ovulation in this dosage. No ovulation was detected in studies over 97% of cycles. This is the most important prevention mechanism.
Zervixschleim thickening: The gestagen makes the slime in the cervical neck thicker and more impenetrable for sperm. This effect occurs quickly and can be measured only a few hours after taking.
**Endometrium Change:* * The cervical mucosa is less developed under the influence of the gestagen.
Advantages over combination pills: Since no estrogen is present, estrogen-related side effects such as water retention, nausea or increased risk of thrombosis are eliminated.
Who is it suitable for?
Cerazette is particularly suitable for:
- Stylish mothers – Desogestrel passes only minimally into breast milk
- **Women with estrogen intolerance * *
- **Smokers over 35 years * *
- **Women with migraine with aura* *
- **Women with increased risk of thrombosis * *
- **Women with estrogen-related complaints * *
Suitable for:
- Still time (from 6 weeks after release)
- estrogen-related side effects under combination pill
- High blood pressure
- Overweight
- Certain cardiovascular diseases
**Be aware of the application:* * Cerazette is not suitable for everyone. It should not be used in certain liver diseases, hormone-dependent tumors or unexplained bleeding.
Available Dosages
Inactive content:
- Desogestrel: 0.075 mg (75 micrograms) per tablet
Pack sizes:
- 1 x 28 tablets (1 month)
- 3 x 28 tablets (3 months)
- 6 x 28 tablets (6 months)
speciality: Unlike combination pills, Cerazette is taken throughout – without a break. All 28 tablets of a pack contain the active ingredient (no placebos).
How to Take
Taking without break: Cerazette is taken every day without 7-day interruption. After the last tablet of a pack, the new pack is started the next day.
Intake date:
- Take every day at about the same time
- The entrance window is 12 hours (bigner than older minipills)
- Suck with some water
Initiation of receipt:
- Without previous hormone prevention: On the first day of the period, immediate protection
- After combination pill: The day after the last tablet or after the break
- After release: from 21-28 days after birth, in the first 7 days additionally prevent
Forget tablet:
- Up to 12 hours too late: Immediately take after, keep protection
- More than 12 hours: Suppression and 7 days additionally with condom
For gastrointestinal complaints: In case of vomiting or diarrhea within 3-4 hours after taking a replacement tablet.
Contraindications
**Cerazette may not be used at:* *
- Consisting or earlier venous thromboemboly (Other than often assumed, this also applies to pure gestagen preparations)
- Smooth liver disease (currently or until normalization of liver values)
- Certified or suspected breast cancer or other hormone-dependent tumors
- **Unexplained vaginal bleeding * *
- ** pregnant * *
- Oversensitivity against desogestrel or other components
Preview at:
- Diabetes mellitus with vascular damage
- Heavy depression (also in prehistory)
- Chloasma (Pigmentflecken) – avoid sun exposure
- Functional ovarian cysts
Advantage: Cerazette can be an option for many contraindications for estrogen (smooths above 35, migraine with aura, certain cardiovascular diseases).
Possible Side Effects
**Very common (more than 10%):* *
- Irregular bleeding or lubrication bleeding (especially in the first months)
- No bleeding (Amenorrhoea)
Acid (1-10%):
- Headaches
- Mood fluctuations, depressive mood
- nausea
- Acne
- Chest pain
- Weight gain
- Reduced libido
** Occasionally (0,1-1%):* *
- Ovarial cysts (usually harmless and form themselves)
- fatigue
- Skin rash
- Hair loss
Selten:
- Heavy allergic reactions
Note on bleeding irregularities: Irregular bleeding is the most common reason for the settling of Cerazette. They usually improve after 3-6 months. About 20% of women have no more bleeding – this is medically safe.
Interactions
Sustainability by:
- Antiepileptics (Phenytoin, Carbamazepine, Phenobarbital, Primidon, Oxcarbazepine, Topiramat)
- Rifampicin, Rifabutin
- HIV drugs (Ritonavir, Nelfinavir)
- Johanniskraut (Hypericum)
- Griseofulvin
Recommendation for interactions: During taking and up to 28 days after placing the interacting drug, additionally prevent it with condoms.
Cerazette can affect:
- Ciclosporin (mirror can rise)
No relevant interaction with:
- Most antibiotics (Amoxicillin, Azithromycin etc.)
- Paracetamol
- Ibuprofen
Active coal: When activated carbon is taken (e.g. in the case of poisoning), the absorption of active substance can be reduced.
Frequently Asked Questions
Similar Medications
Is Cerazette right for you?
A licensed doctor will review your information and issue a prescription if suitable. Discreet and secure.
Important Notice
This information does not replace medical advice. If you have questions about your health or the suitability of this medication, please consult a doctor or pharmacist.
Important Safety Information
This service operates under German pharmaceutical law (HWG). For risks and side effects, read the package leaflet and consult your doctor or pharmacist. All medications are dispensed from a licensed pharmacy in Germany.